Selective METTL1 Inhibitor Extends RNA Target Validation

Company Yankova laboratory (academic) Event Type Peer-reviewed publication Modality Small-molecule RNA-modification enzyme inhibitor Asset STM9005 Target METTL1 (tRNA m7G methyltransferase) Disease Area AML and solid tumors (preclinical) Summary A peer-reviewed Nature paper published online 28 October reports STM9005, a selective catalytic METTL1 inhibitor, with cellular…

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