SPNS2 Loss Exposes a MAPK Sensitive AML State

Company Sodaro laboratory (academic) Event Type Peer-reviewed publication Modality Biomarker-guided MEK inhibition (target-context mapping) Asset SPNS2 expression biomarker Target SPNS2; RAS/MAPK signaling Disease Area Core-binding-factor acute myeloid leukemia Summary A peer-reviewed Nature Communications article published online 28 October links SPNS2 loss to altered sphingomyelin-rich membrane…