Category Deals and Financing

GSK – $1B SiranBio Oligo Deal

Summary GSK has signed an oligonucleotide licensing agreement with China-based SiranBio worth up to $1 billion to develop SA030, a Phase 1-stage ALK7-targeting therapy for metabolic disease and abdominal fat reduction. What Happened GSK agreed to pay SiranBio $55 million…

Takeda – Rusfertide US Rights Deal

Summary Protagonist Therapeutics has opted out of its 50:50 US profit-sharing agreement with Takeda for rusfertide, granting Takeda full US commercial rights in exchange for up to $475 million in near-term payments and substantial downstream milestones and royalties. What Happened…

Lilly – Ajax JAK2 Deal ($2.3B)

Summary Eli Lilly has entered a definitive agreement to acquire Ajax Therapeutics in a deal worth up to $2.3 billion to secure AJ1-11095, a first-in-class Type II JAK2 inhibitor for myelofibrosis and polycythemia vera, positioning Lilly in the next-generation JAK…

Regeneron – MFN Drug Pricing Agreement

Summary Regeneron has entered into a ‘most favored nation’ (MFN) drug-pricing agreement with the White House, aligning certain drug prices with Medicaid benchmarks. The move reflects increasing policy pressure on pharmaceutical pricing rather than a scientific or clinical development. What…

Merck – $1B Google AI Deal

Summary Merck has entered a ~$1 billion enterprise agreement with Google Cloud to expand use of AI across its R&D and operational infrastructure, marking a major investment in AI-enabled drug development capabilities. What Happened Merck signed a long-term deal with…

Beeline Therapeutics – $300M Launch

Summary Beeline Therapeutics has emerged from stealth with approximately $300 million in financing, representing one of the largest recent biotech startup launches and signaling renewed investor appetite for platform-driven company creation. What Happened The Bain-backed company officially launched with ~$300M…

Neomorph – $100M Molecular Glue Financing

Summary Neomorph has raised $100 million to advance its molecular glue platform, reinforcing investor confidence in next-generation targeted protein degradation technologies. What Happened The company secured $100M in financing to expand development of its molecular glue therapeutics platform. The announcement…

Pfizer – SF R&D Site Closure

Summary Pfizer announced the closure of its South San Francisco research site, citing underutilization and broader pressures in the biotech funding environment. The move reflects ongoing post-pandemic restructuring across large pharmaceutical companies and signals shifts in R&D footprint strategy. What…