LNP Editing Preserves Stem Cell Yield in Sickle-Cell Models

Institution: Innovative Genomics Institute · Technology: Lipid Nanoparticle CRISPR Delivery vs. Electroporation · Target: Erythroid BCL11A Enhancer · Application: Sickle Cell Disease · Date: August 30, 2026 Summary A non-peer-reviewed study directly compared Cas9 ribonucleoprotein electroporation with lipid-nanoparticle delivery of Cas9 messenger RNA to disrupt…