CRISPR Off-Target Effects Vary by Cell Type and Organ, Study Finds

Companies: AstraZeneca / Integrated DNA Technologies · Finding: CRISPR Off-Targets Vary by Cell and Organ · Publication: Nature Communications · Date: August 26, 2026 Summary An AstraZeneca- and Integrated DNA Technologies-led Nature Communications study found that CRISPR-Cas9 off-target mutations and balanced translocations can differ across…