Dual-Target PROTAC Suppresses AML in Mouse Model

Institution: University of Florida · Event Type: Peer-Reviewed Preclinical Publication · Modality: Cereblon-Recruiting PROTAC (Celastrol-Derived) · Targets: IKKβ and/or NR4A1 · Disease Area: Acute Myeloid Leukemia · Publication Date: July 30, 2026 (Oncogene) Summary A peer-reviewed Oncogene study describes A9, a celastrol-derived cereblon-recruiting PROTAC that…