Drug Switches Control Engineered CAR T Activity

Company Rihtar and colleagues (academic) Event Type Peer-reviewed publication (source-gap recovery) Modality Small-molecule-regulated CAR-T (ER degron fusions) Asset ER-degron ON/OFF CAR constructs Target CD19; HER2 (model CARs); estrogen-receptor domain Disease Area Cell-therapy engineering (preclinical) Summary An ACS Chemical Biology peer-reviewed paper published online 27 October…