Single-Atom Edits Redirect a Dual Degrader Scaffold

Company Academic Molecular-Editing Consortium Event Type Preclinical Research Findings (Non-Peer-Reviewed Preprint) Modality Targeted Protein Degradation (PROTAC and Molecular Glue) Asset 424-ND (NSD2-Directed PROTAC) and 424-GD (GSPT1 Molecular Glue), Derived From Dual Degrader LLC0424 Target NSD2 and GSPT1 via CRBN-Dependent Ternary Complex Disease Area Prostate Cancer…