tBE Editing Shows Durable Hemoglobin Correction in Four Patients

Evidence Peer-reviewed publication · Published September 7, 2026 · Discovery September 9, 2026 · Importance 5/5 · Direction Positive Summary Investigators reported four recipients of autologous hematopoietic stem and progenitor cells edited ex vivo with tBE, a transformer base editor intended to reactivate fetal hemoglobin.…