CAR-T Persists in Cerebrospinal Fluid After Tisa-cel

Institution: St. Jude Children’s Research Hospital · Product: Tisagenlecleucel (Commercial CD19 CAR-T) · Finding: Long-Term CSF Persistence · Population: Pediatric/Young-Adult B-ALL · Date: September 3, 2026 Summary A St. Jude longitudinal study detected tisagenlecleucel-derived CD19 CAR-T cells in cerebrospinal fluid in 28 of 29 pediatric…