EvoBind Designs Macrocyclic Molecular Glues From Sequence Alone

Consortium: EvoBind-Multimer Academic Team · Modality: Sequence-First Macrocyclic Molecular Glues · Targets: VHL-KRAS, VHL-BRD4 · Date: August 21, 2026 (preprint) Summary EvoBind-multimer is a sequence-first generative framework for designing macrocyclic peptides that bridge an E3 ligase to a chosen target without a known ligand or…